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amoebaa·moe·ba also a·me·ba (ə-mē′bə)n. pl. a·moe·bas or a·moe·bae (-bē) also a·me·bas or a·me·bae Any of various one-celled free-living or parasitic protozoans having no definite form and moving by means of pseudopods.[New Latin Amoeba, genus name, from Greek amoibē, change, from ameibein, to change; see mei- in Indo-European roots.]a·moe′bic (-bĭk) adj.