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amoebaaÂ·moeÂ·ba also aÂ·meÂ·ba Â (ə-mē′bə)n. pl. aÂ·moeÂ·bas or aÂ·moeÂ·bae (-bē) also aÂ·meÂ·bas or aÂ·meÂ·bae Any of various one-celled free-living or parasitic protozoans having no definite form and moving by means of pseudopods.[New Latin Amoeba, genus name, from Greek amoibē, change, from ameibein, to change; see mei- in Indo-European roots.]aÂ·moe′bic (-bĭk) adj.