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barÂ·riÂ·er Â (băr′ē-ər)n.1. A material formation or structure, such as a mountain range or wall, that prevents passage or access.2. Something immaterial that obstructs or impedes: Lack of education can be a barrier to success.3. Physiology A membrane, tissue, or mechanism that blocks the passage of certain substances.4. Ecology A physical or biological factor that limits the migration, interbreeding, or free movement of individuals or populations.5. A movable gate that keeps racehorses in line before the start of a race.6. often barriers The palisades or fences enclosing the lists of a medieval tournament.7. Geology An ice barrier.[Middle English barrer, from Old French barriere, from Vulgar Latin *barrāria, from *barra, bar.]